Medicated Shampoos, Conditioners, Co-washes and Treatments For Itchy Scalp, Dry Scalp, Seborrheic Dermatitis (List)

Below is a list of medicated shampoos and conditioners for troubled scalps, sorted by product type and active ingredients. If you have dry scalp - see the end of this post for ideas (scroll to the end).

Many of these shampoos have herbal ingredients which can either soothe, irritate (or do absolutely nothing). Proteins may soothe a dry scalp, but can also be irritating for some people.
Essential oils like tea tree, rosemary, thyme, sage, (neem oil is going in small letters because it's so stinky) can be antifungal if used in adequate concentrations. But they can also cause sensitivity reactions or allergic reactions.
Sometimes detergents in dandruff shampoos can irritate already-irritated skin, however, there are some detergent-free options in this post and there are medicated conditioners at the bottom of the page for people whose skin or hair does not tolerate detergents. You can wash your hair and scalp with medicated conditioners.
Not everybody with itching will have flakes, not everybody with flakes will have itching. Some people get painful or itchy bumps instead - but the treatments are usually the same.
If you're not getting relief from any of these treatments, you may be reacting badly to fragrances, preservatives or some other ingredient in hair products. Or you may be dehydrating your scalp too much - see the final paragraph after the list.
And if you're trying lots of medicated shampoos and conditioners and topical treatments with no relief, please see a doctor or dermatologist if that is an option available to you. They can prescribe medications that may be more effective.

Lets talk about rotating treatments! If you are a frequent customer in the itchy or flaky or bumpy, scaling, patchy scalp department, there is a good chance you need to have 2 or 3 different medications that work on standby. Why? Because the fungus (Malasezzia) that is strongly implicated in scaling and flaking and itchy, unhappy scalps has many different variations, if not true sub-species, then like sub-species. For example, you might use a zinc pyrithione shampoo and it works now, but it may not work as well later on. It's possible that some fungi on your scalp that were causing the itch and inflammation were not affected by that medication - or they developed some resistance to it. Each medication has a slightly different method of "attacking" fungi and some methods work better on some fungi than others. So if that happens, you need a different medication to control these fungi the next time around. Some fungi will be controlled with zinc pyrithione, others will be controlled with ketoconazole or selenium sulfide. Sometimes sulfur will get the job done and sometimes salicylic acid (with or without sulfur) works best.
Some people need to rotate between different outbreaks or flare-ups. Some people need to rotate every time they wash their hair. It's not fun, but it helps.

If you need to use medicated shampoo often and your scalp is not oily, or all the shampooing dries skin and hair - consider using a medicated conditioner as a "shampoo" - it won't lather but it might provide some relief. If you have dry or curly hair - you might love it.

The Active Ingredients: Look for the listed concentration. If concentration is not listed on the bottle - be wary, but it might still work.
  • Zinc pyrithione: Antifungal, may reduce scaling, may relieve inflammation. Effective at 1%, also effective at 0.5%, response may be slower than 1% (or not).
  • Tar: Slows proliferation of skin cells. Skin cells proliferate too quickly with dandruff - so you end up with scaling and flaking. Effective as 0.5% active tar.
  • Salicylic acid: Anti-scaling (remove scales and reduce flaking), can be anti-inflammatory and anti-septic. Effective at 1% to 1.5% and greater, sensitive skin may need 0.5% to avoid irritation. This exfoliates, so it may help with bumpy cysts if your scalp tolerates it.
  • Selenium sulfide: Antifungal, effective at 1%
  • Sulfur: Mild antifungal and antiseptic, anti-inflammatory, mild exfoliant. Effective at 2%
  • Ketoconazole: Antifungal. Effective at 1%, 2% is the most-effective, prescription dose (non-prescription outside the USA).
  • Tea tree oil: Anti-fungal, anti-septic when the concentration is adequate.
  • Rosemary oil, thyme oil, cedar oils: Anti-fungal, anti-septic, may promote healing.
  • Hydrocortisone: Inflammation is a critical part of the itchy-flaky scalp issue. Hydrocortisone reduces inflammation and relieves itching. Effective at 1%.
  • Piroctone Olamine: Antifungal, Effective at 1% (unless I find otherwise)

Note: This is organized by active ingredients. Also indicated are: Sulfate-free, silicones. Sulfates ("sulfate detergents," a class of anionic detergents) and silicone emollients/detanglers are not necessarily bad for itchy or scaly scalps, but some people avoid them so I'm just trying to help you narrow the field. "Sulfate-free" shampoos are not necessarily milder or non-drying. 

Medicated Shampoos

Tar
  • Denorex Maximum Strength: Tar 1.8%, Sulfate-free
  • Mill Creek Dandruff Control Shampoo:  Tar 0.5%
  • Neutrogena T-Gel: Tar 0.5%

Tea Tree
  • Aubrey Organics, Scalp Rescue Shampoo, Tea Tree & Primrose: Tea tree oil, concentration unspecified: Sulfate Free
  • Jason Normalizing Tea Tree Scalp Normalizing Shampoo: Tea tree oil, concentration unspecified
  • Nature's Gate Tea Tree Calming Shampoo: Tea tree oil, concentration unspecified: Sulfate Free

Zinc Pyrithione
  • AG Control Anti-Dandruff Shampoo : Zinc Pyrithione 2%
  • Aveeno Nourish + Dandruff Control: Zinc Pyrithione 1%, contains silicones
  • Avlon KeraCare Dry & Itchy Scalp Moisturizing Shampoo: Zinc Pyrithione 1%
  • Clear Scalp Therapy shampoo: Zinc Pyrithione 1%, contains silicones
  • Derma Zinc Shampoo: Zinc Pyrithione 2%
  • DHS Zinc Shampoo: Zinc Pyrithione 2%, sulfate-free
  • DS Laboratories Danderene High Performance Anti-Dandruff Shampoo: Zinc Pyrithione 2%: Sulfate Free
  • Dr. Miracle's Cleanse & Condition 2-in-1 Dandruff Shampoo: Zinc Pyrithione 1%
  • Head and Shoulders Shampoos: Zinc Pyrithione 1%, contains silicones
  • Jason Dandruff Relief 2-in-1 Shampoo+Conditioner:  Zinc Pyrithione (concentration unspecified)
  • Kenra Dandruff Shampoo :Zinc Pyrithione 1.9%
  • Mane N Tail Daily Control Anti-Dandruff shampoo: Zinc Pyrithione 1%
  • Matrix Scalptherapie Antidandruff Shampoo:  Zinc Pyrithione (concentration unspecified) contains silicones
  • Neutrogena Daily Control 2-in-1: Zinc Pyrithione 1%, water-insoluble silicone, water-soluble silicone+wheat protein
  • Nioxin Scalp Recovery Cleanser: Zinc Pyrithione 1%, contains silicones
  • Noble Formula ZInc Shampoo: Zinc Pyrithione 2%, fragrance-free
  • Redken Scalp Relief Shampoo: Zinc Pyrithione (concentration unspecified)
  • Suave Dandruff Solutions Anti Dandruff Shampoo Coconut and Shea Butter: Zinc Pyrithione, contains silicones
  • Suave Dandruff Solutions Anti Dandruff Shampoo Mint and Eucalyptus: Zinc Pyrithione,  contains silicones
  • Suave Professionals Men 2-in-1 Classic Clean Anti-Dandruff: Pyrithione 1%, contains silicones
  • Zincon: Zinc Pyrithione 1% sulfate-free

Salicylic acid
  • Avalon Organics Medicated Anti-Dandruff Shampoo: Salicylic acid 2%, 
  • Denorex Extra Strength: Salicylic acid 3%, sulfate-free
  • Giovanni Don't Be Flaky Soothing Anti-Dandruff Shampoo: 2% Salicylic acid: Sulfate Free
  • Home Health Everclean Shampoo: 1.8% Salicylic acid, available in scented and unscented
  • Jason Dandruff Relief Shampoo: Sulfur 2%, Salicylic Acid 2%: Sulfate free
  • Mineral Fusion Anti-Dandruff Shampoo: 2% Salicylic acid: Sulfate Free
  • Neutrogena T-Sal: Salicylic acid 3%, sulfate-free
  • Pure & Basic Anti-Dandruff Shampoo Tea Tree and Rosemary: 2% Salicylic acid, sulfate-free, water-soluble silicone
  • Sebex Shampoo (generic for Sebulex): Salicylic acid 2%, Sulfur 2% 
  • Shea Moisture African Black Soap Deep Cleansing Shampoo: Salicylic acid, concentration unknown, also tea tree oil. Sulfate Free (this contains soap which may or may not leave some residue if you have hard water)
  • Thicker, Fuller Hair Dandruff Sulfate-Free Shampoo: 1.8% Salicylic Acid: Sulfate Free

Sulfur
  • Jason Dandruff Relief Shampoo: Sulfur 2%, Salicylic Acid 2%: Sulfate free
  • Sulfur 8 shampoo: Sulfur
  • Sebex Shampoo (generic for Sebulex): Salicylic acid 2%, Sulfur 2%

Ketoconazole
  • Nizoral: Ketoconazole 1%, sulfate free
  • Regenepure: Ketoconazole 1%, sulfate-free, not suitable for vegetarians
  • Boots Anti-Dandruff Ketoconazole shampoo: Ketoconazole 2% - this is a UK brand

Selenium sulfide

  • Head And Shoulders Clinical Strength: Selenium sulfide 1%, silicone
  • Selsun Blue Medicated Dandruff Shampoo: Selenium sulfide 1%

Hydrocortisone
  • Dr. Marder's Total Relief Shampoo: 1% Hydrocortisone, Sulfate-free
    • See the "Spray, liquids, gels and DIY list below for more treatments with hydrocortisone
Piroctone Olamine
  • Alpecin Dandruff Killer Shampoo, also contains salicylic acid and zinc pyrithione
  • Pilfood Dandruff Shampoo 
  • SebaMed Anti Dandruff Shampoo 
  • Hegor Shampoo for Persistent Dandruff (European brand): Piroctone Olamine and Pyrithione zinc
  • Davine's Natural Tech Purifying Gel: Zinc Pyrithione 0.48%, Piroctone Olamine


Medicated Conditioners and Co-washes: 
  • Avalon Organics Medicated Anti-Dandruff Conditioner: Salicylic acid 2%
  • Avlon KeraCare Dry & Itchy Scalp Moisturizing Conditioner: Zinc Pyrithione 1%, Contains silicone
  • Dr. Marder's Total Relief Conditioner: Zinc Pyrithione 1%contains an "evaporating" silicone - less likely to build up on hair
  • Giovanni Don't Be Flaky Nourishing Conditioner: Salicylic acid 2%
  • Head and Shoulders Conditioners - not "2-in-1 shampoo plus conditioner," that is shampoo (Itchy Scalp Care, Classic Clean, Damage Rescue, Green apple, Instant Relief): Zinc Pyrithione 0.5%contains silicones
  • Head and Shoulders Moisture Care Co-Wash: Zinc Pyrithione 0.5% Contains silicone
  • Jason Normalizing Tea Tree Conditioner: Tea tree oil, concentration unspecified
  • Mane N Tail Daily Control Anti-Dandruff Conditioner:  Zinc Pyrithionecontains silicone
  • Nature's Gate Tea Tree Calming Conditioner: Tea tree oil, concentration unspecified
  • Suave Scalp Solutions Anti-Dandruff conditioner Coconut and Shea butter: Zinc Pyrithione, contains silicone
  • Sulfur 8 Medicated Light and Original formula hair/Scalp conditioner: 2% sulfur - this is not a creamy hair conditioner, it is petrolatum-based
  • Shea Moisture African Black Soap Purification Masque: Salicylic acid, concentration unspecified, also neem and tea tree oil, concentration unspecified
  • Shea Moisture African Black Soap Balancing Conditioner: Salicylic acid, concentration unspecified, tea tree oil, concentration unspecified
  • Yes To Carrots Scalp Relief Conditioner: Tea tree oil, concentration unspecified, Salicylic acid, concentration unspecified 

Non-Shampo Sprays, Liquids, topical gels or creams and DIY treatments:
  • Davine's Natural Tech Purifying Gel: Zinc Pyrithione 0.48%, Piroctone Olamine
  • Derma Zinc Cream: Zinc Pyrithione 0.25%
  • Essential oil treatments, mixed into oil and left on for a little while before washing, or mixed into your favorite shampoo:
    • Mix 3-5 drops of tea tree oil or rosemary essential oil or thyme essential oil or cedar essential oil into 1 tablespoon (15 ml) of oil such as olive oil. Apply to the scalp, leave on 10-30 minutes and shampoo out. 
    • Mix 3-5 drops of tea tree oil or rosemary essential oil or thyme essential oil or cedar essential oil into 1 tablespoon (15 ml) of shampoo or conditioner and use as you normally would - allow the shampoo or conditioner to stay on your scalp for several minutes before rinsing.
    • 3-5 drops of essential oil = up to 1/16th of a teaspoon, 0.15 ml-0.25 ml
  • Miconazole nitrate creams (for the scalp is an off-label use as an anti-fungal, use at your own discretion)
  • Noble Formula Zinc cream: Zinc Pyrithione 0.25%
  • Psoriasin gel: Tar 1.25%
  • Scalpicin 2-in-1: Salicylic acid 3%
  • Scalpicin Maximum Strength: Hydrocortisone 1%
  • Selsun Blue Scalp Itch Treatment: Hydrocortisone 1%
  • Shea Moisture African Black Soap Dandruff and Dry Scalp Elixir (Spray for the scalp): Salicylic acid, concentration unspecified, tea tree oil concentration unspecified
  • Tolnaftate Creams or liquid (for the scalp is an off-label use, use at your own discretion)


    DRY SCALP? Got an especially dry or itchy scalp? Scalp needs soothing? 

    • Wash only as often as you need to to keep ahead of itching. Just wetting and drying our skin creates irritation, so don't wash your hair/scalp unless it's dirty or looks bad or is getting more itchy when you don't wash it.
    • Look for balanced shampoos and conditioners. "Balanced" in a shampoo means:

    1. Look for more than 1 detergent (that makes it milder). For example, sodium lauryl sulfate + cocamidopropyl betaine or C14-16 Olefin sulfonate + cocamidopropyl betaine; any of these + decyl glucoside, or combined with Sodium Cocoyl Isethionate
    2. You probably want some conditioning ingredients like cetrimonium chloride, polyquaternium ingredients, some emollients like plant oils or glycol distearate, sucrose cocoate, PEG-cocoate or silicones to soften skin make detergent less irritating.
    3. You also want humectant ingredients which can act as anti-irritants that will help your scalp retain moisture and reduce irritation like polyquaternium-7, panthenol, sodium PCA, glycerin, hydroxypropyltrimonium honey, aloe, propanediol, glycine betaine, urea or allantoin.  These can be great for your hair too. 
    4. In conditioners (if you put those on your scalp), look for the same things - aside from conditioning ingredients, look for those irritation-reducing humectants to round out protection for your scalp.
    5. Try applying some oil (avocado, olive, jojoba...) to your scalp or a little fragrance-free skin lotion 10 minutes before you wash your hair. This softens the skin and protects it from the drying effects of washing. CAUTION: If you have a fungal component to your scalp troubles, oil can make it worse. Dry scalp can actually be a by-product of an "ecosystem imbalance."

    If you live in a dry or windy area, protect your scalp from the wind because that can be so drying to skin - even a light scarf provides a good barrier.

    Related Posts:

    What's Cookin' - Easy Humectant Curl Defining Jelly-Cream

    This is based on my Easy Humectant Curl Boosting Jelly recipe and inspired by reader comments, and by the problem some of us have with glycerin in winter or dry weather. It's a light-hold curl and wave definer. This recipe is very easy to make. 

    What's new?
    -Addition of your choice of emollient blend to make this creamy for softness and lubrication (oil+plant butter or oil+conditioner). 
    -Increased acacia gum to keep the definition in waves, curls and coils. 
    -Options for humectants for those who avoid glycerin.
    -Adjust the amount of emollients (oils, butters, conditioners) to suit 1) your hair's needs and 2) the amount of "hold" you want (see below)

    The ingredients:
    -Water: Solvent, dliutent
    -Xanthan gum: Creates a thick "gel," provides medium hold with humidity-resistance, may slow water loss.
    -Humectant of your choice. Glycerin(e), or hydrolyzed protein, or panthenol or Hydroxypropylrtimonium honey (honeyquat) or a combination of these: Humectants bind water, boost curls, maintain hydration. NOTE: Panthenol is sold as a cosmetic additive, hydrolyzed proteins are sold as cosmetic additives but are also more widely available as products like Neutral Protein Filler and Green Beauty Products Real Protein. Hydroxypropylrtimonium honey is sold as a cosmetics additive.
    -Acacia gum (gum arabic): Adds a bit of "crunch" for more hold, helps emulsify the oils. This powder is sold as a dietary soluble fiber supplement and also sold as a cosmetics ingredient.
    -Emollient: Shea butter (or cocoa butter, mango butter or whichever butter you prefer) OR commercial hair conditioner
    -Oil: Jojoba oil OR grapeseed oil OR any oil you prefer (avocado, olive, sweet almond, rose hip, etc.)

    I use a double boiler to control the heat for this recipe. 
    The gel, before adding any oils or butter blends or conditioner.
    ©Science-y Hair Blog 2013
    The recipe:
    • 1 cup water (plus an extra tablespoon or 2 which will evaporate as you heat). 230 ml
    • 1 1/4 teaspoons xanthan gum (2% or 5g or 6.15 ml)
    • 1/4 to 1/2 teaspoon acacia gum (gum arabic) - more for more hold or if you use more emollients (0.6g to 1.25g, 1.25 to 2.5 ml)
    • Shea butter and jojoba oil as your hair requires (see "How much butter blend to use" below) OR oil and commercial hair conditioner blend
    • Humectant options: 1/2 teaspoon glycerin - make this a scant half-teaspoon; more than 1/4 teaspoon, less than 1/2 teaspoon (1% or 2.5 g, or 2.5 ml)
      • Instead of glycerin: 1/2 teaspoon liquid panthenol or 1/4 teaspoon powderedpanthenol, or 1/2 teaspoon hydrolyzed protein or protein additive or 1/2 teaspoon "Honeyquat" (Hydroxypropyltrimonium honey).

    1) Make the oil blend (If you are using oil and conditioner instead of butters, skip this step)
    Measure out 2 parts liquid jojoba oil (or an oil of your choice) to 1 part solid shea butter. Either combine these in a bowl and place in a larger bowl of warm water to melt, or add to the heated, prepared gel to melt.

    How much butter blend or conditioner/oil to use? 
    • To keep the most hold (or for silky, not-dry hair): 1/4 to 1/2 teaspoon (1.25 to 2.5 ml)
    • Hair that needs extra flexibility and does not get oily-looking easily: 1 to 3 teaspoons (5 to 15 ml)
    • Hair that really loves oils and butters: 3 teaspoons to 3 tablespoons (15 to 45 ml)

    2) Make the gel
    Put water, xanthan gum and acacia gum the double boiler over medium to high heat. When water boils, turn it down. Whisk the ingredients well throughout the heating time. The mixture will thicken right away, but it is not finished yet. Whisk until no more xanthan gum powder is visible and the gel goes from thick and heavy to smoother, less stiff and easier to stir. Turn off heat. 

    3) Add the oil/butter blend or oil and conditioner
    For oil/butter blend: Add the melted oils or liquid jojoba oil and solid shea butter to the warm gel and allow it to melt as you mix. Mix well with a fork or whisk to combine oil and gel. If you like, use an immersion blender. Once well blended, remove from heat and cool to a touchable temperature.
    For oil and conditioner: Add equal parts oil and conditioner to the cooled (comfortable to touch the bowl) gel and mix well

    4) Add humectant
    Mix the glycerin or hydrolyzed protein or panthenol or honeyquat into the cooled gel.

    Scoop into a sterilized bottle and refrigerate immediately - or add preservative according to manufacturer specifications. Xanthan gum is anionic; check that preservatives are compatible with anionic ingredients.
    ©Science-y Hair Blog 2013
    Recipe Variations (other additives and ingredient substitutes)
    • Magnesium sulfate (1/2 teaspoon) - this is a humectant and curl enhancer but it can be drying to hair.
    • Aloe. Replace up to half of the water with aloe vera juice - the edible/drinkable kind, not a pre-thickened gel.
    • If shea butter makes your hair look dull and waxy, skip the butter and use liquid oils only. 
    • Agave nectar - provides hold, especially in dry weather. Adds shine. Use 1/4 to 1 teaspoon.

    Need more hold?

    Mix equal parts of this curl definer with your favorite stronger-hold styling gel. It has mixed well with the gel I mixed it with, which is a basic hair gel similar to Ecostyler or LA Looks or Salon Care gels.

    Related Posts: